Category Archives: Kidney

The Yeshiva World Gaza Child Undergoes a Transplant in Rambam Medical Center « » Frum Jewish News

(Tuesday, September 9th, 2014)

16Once again, a Gazan resident benefits from Israeli medical technology. For years, M, a 14 year-old-boy from Gaza suffered from kidney failure. Recently, the youth’s doctor informed his family that without a transplant, the boy’s life would be at great risk. Exacerbating his condition, M’s blood also coagulated too easily, reducing the chance of a successful transplant. Against all odds, with the donation of a kidney from his sister, doctors at Haifa’s Rambam Medical Center saved the boy’s life.

M urgently needed a kidney transplant, but his blood condition had obstructed all blood vessels in his groin except the one vein through which he received dialysis. This significantly lowered chances for a successful transplantation.

Doctors explained to M’s family that it was only a matter of time before the final vein would also clog up, preventing dialysis and greatly threatening the boy’s life. To save him, his sister decided to donate a kidney.

Eight years ago, the boy had received a kidney donation from his brother, but the transplant, performed in Egypt, failed immediately. In light of this situation, Rambam doctors made it clear to the family that M’s chances for success were especially low. Despite this, his sister insisted upon the donation.

Considering the state of M’s blood vessels, the doctors were faced with a great challenge. In a regular transplant, doctors remove the donor’s kidney and then connect it to the recipient’s blood vessels. In M’s case, the doctors feared they wouldn’t find healthy blood vessels that could feed the transplanted kidney.

As a result, the doctors worked ‘in reverse’: first, they operated on M and checked for useable blood vessels. Finding a few, they then removed one of his sister’s kidneys and transplanted it in within M.

To compensate for all the blocked veins, M’s body had developed a system of bypass veins. Shortly after surgery, it became apparent that this collateral network could not stand up to the demands of the transplant.

Two hours after leaving the operating room, the youth was returned there. Examinations revealed that all vascular connections performed by Rambam doctors were working, but M’s own blood vessels were not sustaining the transplanted kidney.

The Rambam medical staff had never been confronted with such a situation before. “It was a nightmare scenario,” said Dr. Ran Steinberg, head of Pediatric Surgery. To solve the problem, the doctors implanted a synthetic connector between the vein exiting the kidney and the one that exits the liver.

This innovation worked and M’s body was able to function with the new kidney. After an eight-month stay in Rambam, the boy recently went home to Gaza, and will return for periodic check-ups.

“There are no words to describe the excitement of triumphing in an impossible situation. Not everyone believed we would succeed,” said Dr. Steinberg. “As soon as M started to recover, our doctors’ smiles returned. M is a great kid and he will be able to enjoy the regular life of any child his age.”

(YWN – Israel Desk, Jerusalem / Photo: Rambam Medical Center)

via The Yeshiva World Gaza Child Undergoes a Transplant in Rambam Medical Center « » Frum Jewish News.

European Commission : CORDIS : News and Events : New drug tackles transplant complications

To reduce the number of discards and thus make more kidneys available, researchers and medical scientists from the European consortium MABSOT have created a new drug called OPN-305 to reduce inflammation of the donor organ after transplantation.

Every year nearly 50.000 dialysis patients worldwide receive a kidney transplant, but depending on the type of donor between 20 to 60% of the implanted kidneys are not working. The reason: a complication called “Delayed graft function” (DGF) which can even lead to acute rejection and organ failure.

Now researchers from the MABSOT (Monoclonal Antibody Solid Organ Transplantation consortium) are putting their forces together to minimize the incidences of DGF. Opsona Theurapeutics in Dublin, Ireland, developed a new drug called OPN-305. The humanized protein is directly active against the TLR-receptor 2, which is involved in the inflammatory response triggering DGF during transplantation.

The first clinical trial, with 139 patients from Europe and the USA, seem promising. If the results are successful, in the future the new therapy could not only be used in renal transplantation, but also in heart, lung or other solid organ transplantation.

Watch video: http://www.youris.com/Health/HEALTHTV/New-Drug-Tackles-Transplant-Complications.kl#ixzz3CAWzSd00

via European Commission : CORDIS : News and Events : New drug tackles transplant complications.

Discordance between patient and provider in discussions about kidney transplantation – Medical News Today

Last updated: 1 September 2014 at 12am PST

In a study of dialysis patients, those who reported that they had discussed the option of transplantation with clinicians were more likely to be put on the transplant waiting list; however, clinician-reported discussions of transplantation did not increase patients’ likelihood of being waitlisted. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), indicate that better ways of informing patients about kidney transplantation may be needed.

One of the key principles of informed consent is describing alternative treatments. So when starting someone on hemodialysis, it is imperative to discuss the alternatives to hemodialysis, for example peritoneal dialysis and kidney transplantation. The Centers for Medicare & Medicaid Services (CMS) believe the discussion of kidney transplantation is so important that they mandate it. Unfortunately, though, there is no guidance as to what kind of discussion is required.

Dorry Segev, MD, PhD (Johns Hopkins University School of Public Health) and his colleagues asked 388 patients if providers (kidney specialists or dialysis staff) had discussed transplantation with them, and then they looked to see whether the providers reported to CMS that they had discussed transplantation with those patients.

The investigators discovered that in almost one-third of cases, providers reported to CMS that they had discussed transplantation with a particular patient, but the patient said that nobody had discussed it with them. Such discussions were reported by both patient and provider for 56.2% of participants, by provider only for 27.8%, by patient only for 8.3%, and by neither for 7.7%.

The researchers also discovered that patient-reported discussions about transplantation were associated with a nearly 3-fold increased likelihood that patients would be listed for transplantation, but provider-reported discussions did not increase a patient’s likelihood of being listed. In other words, it didn’t matter if the provider reported discussing transplantation with the patient; it was only if the patient reported receiving this information that led to him or her to being referred for and listed for a transplant.

“This is a critical lesson for quality improvement in the care of patients with end-stage kidney disease: it’s not enough to ask physicians if they provided information to the patient, but rather we need to be asking the patient, because there is major discordance between patient and provider reports, and only the patient report was associated with the expected clinical behavior,” said Dr. Segev.

In an accompanying editorial, Mark Unruh, MD (University of New Mexico School of Medicine) and Mary Amanda Dew, PhD (University of Pittsburgh School of Medicine and Medical Center) noted that that “even the best educational efforts will be for naught if the patient does not take in the information or understand it.” They cautioned, however, that the form submitted to CMS has been recognized as providing an important but inexact snapshot of patients with kidney failure and other conditions. They also stressed that providing kidney transplant information likely requires repeated discussions when patients are open and able to receive it.

via Discordance between patient and provider in discussions about kidney transplantation – Medical News Today.

Toddler ready for kidney transplant

By Amanda Head
For The Times
POSTED: August 10, 2014 1:00 a.m

After waiting a couple of years, little Mason Hyde has reached all of the milestones, including a desired weight and finding a donor, required for a kidney transplant.

“It’s taking a while for him to get his transplant,” said Randi Hyde, his mother. “But to me, it doesn’t seem too far because I’ve done this for years, so I’m happy with a couple months.”

Mason, who was born prematurely nearly three years ago, has a heart condition that causes oxygenated blood to mix with the deoxygenated blood in the heart. Nearly two weeks after his birth, he was sent home with hospice care.

Not expected to live past a few days, and certainly not months, Mason has undergone three heart surgeries and many other operations.

“If we have an emergency, we go straight to Egleston (Hospital in Atlanta),” Hyde said. “Because if anything goes wrong, the doctors he needs are there. We don’t take any chances.”

Mason has awaited a kidney transplant since he started dialysis in July 2012.

“The transplant is the light at the end of the tunnel,” Hyde said. “But he’s progressing better without the transplant than they expected him to.”

Last year, the Hydes were informed Mason’s father, Bobby, was a donor match. However, they recently found out he could have possible kidney issues in the future.

“He had some tests done and he had something going on to where he may have kidney failure later in life,” Hyde said.

Through word-of-mouth and social media, a woman in her late 20s contacted the Hyde family to say she wanted to be a donor.

After finding out she was a match, she began the tests, all of which have been really good, Hyde said.

“It would be extremely hard to find a match for Mason because he has had over 20 blood transfusions,” she said. “It was amazing that she just called and happens to be the perfect match.”

The transplant is scheduled for October. Mason could be at the hospital for up to a month and possibly on several medications afterward.

This year Mason has been resuscitated twice and has been put on oxygen.

“I panic just because last time (he was put to sleep for a surgery earlier this year), he didn’t wake up. And then a week later he stopped breathing on us,” his mother said.

The Hydes are looking forward to their son being able to play on a playground with other kids, having more energy and making fewer trips to Atlanta.

“He’s going to live to be an old grandpa,” Hyde said. “Words can’t express how grateful I am he is still here. It’s a blessing straight from God.”

After the transplant, everything should improve and he should be a completely different child physically, Hyde said. And he should have all good days.

“Unless he’s in trouble,” added his older brother, Trinity Hyde.

via Toddler ready for kidney transplant.

Tocilizumab Research Could Lead to Personalized Treatments for Kidney Transplant Patients

Eileen Oldfield, Associate Editor

Published Online: Saturday, August 9, 2014

A multicenter study will examine whether a drug used to treat rheumatoid arthritis can improve kidney transplant patients’ health.

Researchers from several medical centers will use rheumatoid arthritis drug tocilizumab in a study to determine whether the drug improves kidney transplant patients’ long-term survival. The study will include 2 clinical trials.

The research focuses on regulatory T cells (Tregs), lymphocytes that suppress activity in other immune cells, a press release from the University of California, San Francisco, stated. Normally, Tregs maintain the immune system’s normal homeostasis and safeguard against autoimmune diseases. Researchers hope to induce long-term donor-specific tolerance without impeding immune response to pathogens and tumors in transplant patients.

Preclinical studies show that the cells can be used to control responses in graft-versus-host disease; however, additional research on Treg reactivity, dosing, adjunct immunosuppression, and infusion timing is needed.

The goal is to control inflammation in kidney transplant recipients by increasing the number or activity of Tregs by either infusing the cells into the body or by using tocilizumab to block the inflammatory effects of interleukin 6, the press release stated.

The results of small patient studies suggest a significant, sustained increase in Tregs following tocilizumab treatment, leading to the theory that the drug will increase Treg population in patients who received kidney transplants.

The National Institutes of Health will fund this 7-year, $17-million study investigating the therapy. In addition to the University of California, San Francisco, the University of Alabama at Birmingham, Emory University, and Cedars-Sinai Medical Center will participate in the research.

Although transplantation advances have reduced early acute rejection rates and improved 1-year graft survival, long-term graft success rates remain unchanged. The reasons for the flat long-term success rates include interstitial fibrosis progression and tubular atrophy in the kidney.

According to principal investigator Flavio Vincenti, MD, UCSF professor of medicine, the research holds the promise of personalized treatments for transplant patients.

“This grant allows us to work toward achieving 2 important advances in the transplant field,” Dr. Vincenti said. “We can introduce personalized medicine by treating patients based on molecular profiling of their kidney. We also can allow control of the response to the transplant by the patient’s own immune systems by regulatory T cells, either through infusions or pharmacologically.”

via Tocilizumab Research Could Lead to Personalized Treatments for Kidney Transplant Patients.

Horlick’s former female football player recovering after transplant

August 08, 2014 5:47 pm  •  PETE WICKLUND pete.wicklund@journaltimes.com(1) Comments

Family Encourages People to Become Donors

As 18-year-old Abbi Strack recovers from a kidney transplant, she and her family are asking people to consider registering as potential organ donors.

Her father, John, said that commitment could be as simple as filling out the organ donor registry for your driver’s license, or by getting more information from the National Kidney Foundation, www.kidney.org, or contacting Shelley Chapman, the kidney transplant coordinator at Children’s Hospital of Wisconsin, at schapman@chw.org.

WAUWATOSA — Abbi Strack has faced hurdles before in her young life, including breaking the gender barrier as a four-year player with Horlick High School’s football program.

On Friday, she was enduring pain — but doing well — in the aftermath of a kidney transplant at Children’s Hospital of Wisconsin, her father John, a principal at Horlick, said.

Events leading up to the surgery unfolded quickly, John Strack said, with Abbi, 18, being put on the recipient list for a transplant on June 17 and the family being notified Thursday night to report to the hospital to prepare for the operation early Friday.

John Strack said his daughter was born with one of her kidneys being about one-third of the size of the other, leaving the dominant kidney handling the bulk of the work for Abbi’s system. In the third grade, Abbi underwent surgery to move the ducts that move urine between the kidneys and bladder. In the seventh grade, she was again hospitalized due to heart problems brought on by high blood pressure related to her condition.

Between that health crisis and Friday’s surgery, there was nothing major, John Strack said. Abbi kept up an active teenage life. In addition to her football participation, she played softball for most of her high school career, was an honor student and participated in choir. Outside of school, she was active in Job’s Daughters, the youth wing of the Freemasons for girls, and was named a chapter sweetheart of the Racine chapter of DeMolay, the boys organization for the Freemasons.

But shortly after winter holiday season, Abbi’s health began to decline, John Strack said. She tried to keep her schedule going, even continuing with softball, but had to quit the team after three games because her stamina was gone. In June, Abbi was outfitted with the apparatus needed for dialysis and was just days away from undergoing her first dialysis treatment when the call for the transplant came, John Strack said.

Along with her dad, with Abbi at the hospital on Friday was her mom, Jan, a nurse; and brothers John Jr., 23, and Branden, 19, who are both in the Army. A third brother, Taylor, 22, who is also in the Army, was expected to arrive before today at the hospital.

John Strack Sr. gave thanks and praise to the Army and especially the Red Cross in arranging emergency leaves for his sons.

Also at Abbi’s side was her boyfriend, Jason Hilderbrand, 24, of Burlington. John Strack said Abbi and Hilderbrand met through mutual friends.

The next days will be crucial for Abbi, John Strack said, as medical staff watch for signs of rejection of the new kidney. She will be in the intensive care unit for at least four days and then will continue on in a regular hospital room for a few days before a month of in-home rest. John Strack said that visits to Abbi are restricted and well-wishers are asked not to send flowers or items containing latex to the hospital.

John Strack said that social workers at the hospital are working with officials at the University of Wisconsin-Milwaukee, where Abbi plans to start nursing studies this fall, to try to keep Abbi’s studies on schedule. For updates on Abbi’s condition, visit www.facebook.com/Abbischallenge.

via Horlick’s former female football player recovering after transplant.

Reunion after 38 years for transplant pioneers – Yorkshire Post

A TRANSPLANT patient who underwent a pioneering operation in Leeds has been reunited with her surgeon – 38 years on.

Ruth Moorhead was a teenager when she was the first child to undergo a kidney transplant at St James’s Hospital in January 1976.

In a double first, she received the organ from her father Mervyn – the hospital’s first operation using a live kidney donor.

Ruth – now Ruth Wright – and her parents travelled from their homes in Plymouth to Leeds to meet surgeon Dr Stanley Rosen.

He flew in from California for a special event for former kidney transplant patients and said it was an “immense pleasure” to meet Ruth and fellow transplantees.

Mrs Wright lived in York at the time of her operation, and she and her father, now 87, and mother Beryl brought scrapbooks of press cuttings, letters and mementoes to Leeds.

The family were also reunited with Fred Gungaram, a former nurse who cared for her during her treatment.

Meanwhile another former transplant patient, Charlotte Tate, has marked the anniversary of her lifesaving surgery.

Mrs Tate, previously Charlotte Rogerson, had a heart transplant 20 years ago while she lived in Leeds, but now lives in Northumberland.

via Reunion after 38 years for transplant pioneers – Yorkshire Post.

10-year-old receives life-saving transplant – KTTC Rochester, Austin, Mason City News, Weather and Sports

KTTC Rochester, Austin, Mason City News, Weather and Sports

Posted: Aug 05, 2014 5:33 PM

Updated: Aug 06, 2014 6:43 AM

By Courtney Sturgeon, Reporter – email

MINNEAPOLIS (KTTC) — A 10-year-old Wisconsin boy is getting a life-saving transplant months after his family in Rochester built a giant snowman seeking a kidney for him.

Cathy Santiago, Levi Cooper’s cousin, and her two sons built a nine-foot-tall snowman in their front yard in February. Levi’s story was attached to the snowman along with a plea for a kidney donor.

Since then, Levi and his family, have been staying at the Ronald McDonald House in Minneapolis while he’s been on dialysis awaiting a kidney. The Cooper family is from Spooner, Wisconsin.

Levi’s donor is a teacher at Levi’s elementary school. She heard about Levi’s need from a flier posted at the school. Although she didn’t hear about it from the snowman, Levi’s mom, Rana, said the frosty-inspired creation may inspire others to donate. “This has got to get the word out there,” said Rana Cooper. “We just wanted to get done with dialysis and to see that big snowman and know she did that just for Levi, I love her for doing that.”

Levi has had 54 surgeries since he was diagnosed with Prune Belly Syndrome while he was still in the womb. Prune Belly Syndrome affects about 1 in every 40,000 births.

“He is just a trooper through it all,” said Rana Cooper. “He pops out of surgeries like nothing ever happened.”

Levi said the worst part about surgery is getting stuck with a needle. “I just hold my mom’s hand and I be brave,” said Levi.

“It’s like a miracle knowing that come tomorrow, we’re going to be able to start a new journey and he’s going to feel better and no more dialysis,” said Rana Cooper.

Levi Cooper will be receiving his transplant on Wednesday, August 6 at the University of Minnesota Children’s Hospital in Minneapolis.

via 10-year-old receives life-saving transplant – KTTC Rochester, Austin, Mason City News, Weather and Sports.

UAB – UAB News – $17 million multi-institutional grant to maximize kidney transplant survival

by Tyler Greer

August 04, 2014 Print Email

The University of Alabama at Birmingham is participating in a new seven-year, $17 million multicenter study funded by the National Institutes of Health to determine whether certain immune system cells and/or a drug used for treating rheumatoid arthritis can improve and maintain the long-term health of kidney transplant recipients.

The goal of the study is to reduce or eliminate inflammation in kidney transplants and prevent the associated decline in graft function, thereby maximizing long-term organ survival. It will involve two clinical trials in parallel by researchers at four sites around the country.

Roslyn Mannon, M.D., professor in the School Medicine in the Division of Nephrology and professor of surgery in the Division of Transplantation, is the principal investigator for the grant at UAB. University of California, San Francisco is the lead institution for the study.

Mannon, director of research for the Comprehensive Transplant Institute and immediate past president of the American Society of Transplantation, says the newly funded series of trials to take place at UAB will involve the use of regulatory T cells, or Tregs, and the use of an anti-IL6 receptor antibody. The programs are expected to begin this fall.

“We have been a site for NIH and Clinical Trials in Organ Transplantation studies since 2009,” said Mannon, also a member of the NIH steering committee for the CTOT and a member of the mechanistic studies committee. “In the current funded projects, we collaborate with other institutions on three clinical trials devoted to kidney transplant patients. We have 27 UAB patients enrolled to study a novel combination of immunosuppression with a total of 65 enrolled in all three sites. Additionally, one study is specifically for kidney and pancreas transplant recipients, and is one of the first studies in this patient population to be performed in the past 15 years. To be a part of this new multicenter study is great news. We will continue to participate in these cutting-edge national research efforts.”

Despite advances in transplantation — reducing early acute rejection rates to less than 15 percent and improving one-year graft survival to more than 90 percent — long-term graft success rates have remained unchanged at 4 percent loss annually. A major contributor is the progression of interstitial fibrosis and tubular atrophy in the kidney.

The Comprehensive Transplant Institute provides a means to expand patient options, including incompatible transplantation and kidney-paired donation and new access to transplants for patients with HIV or hepatitis C infection. Every gift will help expand UAB’s expertise in transplant immunology, transplant pathology, and outcomes research, which will have a direct impact on patient care. The cells that the researchers are focused on are Tregs, a small population of lymphocytes that suppress the activity of other immune cells. They maintain normal immune system homeostasis and safeguard against autoimmune diseases, and their immunosuppressive properties also can be harnessed to control transplant rejection.

Tregs have the potential to induce long-term donor-specific tolerance without impeding desired immune responses to pathogens and tumors in transplant patients.

The principal investigator of the study is Flavio Vincenti, M.D., UCSF professor of medicine and a kidney and pancreas transplant specialist at UCSF Medical Center. Other participating institutions are Emory University and Cedars-Sinai Medical Center.

“This grant allows us to work toward achieving two important advances in the transplant field,” said Vincenti. “We can introduce personalized medicine by treating patients based on molecular profiling of their kidney. We also can allow control of the response to the transplant by the patients’ own immune systems by regulatory T cells, either through infusions or pharmacologically.”

Researchers believe inflammation can be controlled in kidney transplant recipients by increasing the number or activity of Tregs, either by infusing them into the body or by blocking interleukin 6 (IL6) with the drug tocilizumab.

To do so, they will conduct two clinical trials — Treg Adaptive therapy in Subclinical inflammation in Kidney transplantation, or TASK, and Therapy to Reduce Allograft Inflammation with IL6 inhibition, called TRAIL.

The trials will involve expert clinical investigators, translational Treg biologists and mechanistic core researchers. The four selected transplant centers are noted for high-quality patient care, high patient volume and the necessary translational infrastructure to ensure successful recruitment. In fact, there already are pre-existing, productive working relationships among the transplant centers and investigators.

Learn more on UAB’s research efforts to help transplanted patients keep their organ permanently and listen to Mannon’s podcast on kidney research at UAB’s The Mix.

via UAB – UAB News – $17 million multi-institutional grant to maximize kidney transplant survival.

Fundraisers set for double kidney transplant recipient – Loveland Reporter-Herald

By Shelley Widhalm

Reporter-Herald Staff Writer

POSTED:   08/02/2014 11:05:05 AM MDT

Jacob Whitler, 16, takes his dog named Buddy for a walk Friday morning near his home in Loveland. Whitler had a kidney transplant a month ago with his mother, Lisa Whitler, as the donor. (Steve Stoner / Loveland Reporter-Herald)

Lisa Whitler talks about the surgeries that she and her 16-year-old son, Jacob, underwent recently when she donated a kidney to Jacob. (Steve Stoner / Loveland Reporter-Herald)

If you go

What: Fundraising event in honor of Jacob Whitler.

When: Thursday, Aug. 7.

Where: Texas Roadhouse, 4633 S. Timberline Road, Fort Collins.

Benefit: 20 percent of sales will be donated, a flier advertising the event is required; go to http://cotaforjacobw.com/node/315.

Other events:

• Sept. 13, Mums sale, preorder perennial flowers and pick them up at the Foundations Church parking lot, 1380 Denver Ave.

• Oct. 19, Bowling tournament, Sweetheart Lanes, 2320 N. Lincoln Ave., Loveland. RSVP by Oct. 5.

To make a donation: Mail it to the Children’s Organ Transplant Association, 2501 W. COTA Drive, Bloomington, IN 47403, or online at COTAforJacobW.com. Checks or money orders should be made payable to COTA with “In Honor of Jacob W” written on the memo line of the check.

Sixteen-year-old Jacob Whitler said about his mother, Lisa, “All I can do is thank her and kiss her feet.”

Lisa donated one of her kidneys to Jacob, who was diagnosed with kidney failure as a baby and got corrective surgery but late last year started experiencing declining kidney function.

“I wanted to give him a new life. I wanted to give him the best chance at the most normal life possible,” said Lisa, a Loveland resident, about her son, who will be a junior at Mountain View High School.

Knowing how high the associated expenses are with a kidney transplant, Lisa’s friends organized a fundraising account on Jacob’s behalf through the Children’s Organ Transplant Association, a Bloomington, Ind.-based nonprofit focused on offsetting transplant-related expenses.

Donations are made to COTA on the patient’s behalf and used to cover expenses such as travel and hotel costs, co-payments and anti-rejection medications that are not covered by health insurance.

Family friend Karen Klein wanted to help Jacob and Lisa, who is a single mother of two children, so she agreed to do the publicity for the fundraising efforts.

“Some people you meet and you just have a connection,” Karen said. “You have a friendship, and you love each other.”

Jacob said when he hears Karen’s name, “I just get happy.”

“Karen’s been a second mother to me for lots of years. She’s always been there for me and my family,” he said.

The COTA fundraiser on Jacob’s behalf is for $45,000 and, with the help of several community members who did their own fundraisers, the effort has raised $14,000 so far. The fundraising, initiated June 1 to continue through May 31, 2015, has included portions of restaurant sales, a jewelry party, a card-making class and a bake sale.

“It’s just amazing that people we know and people we don’t know have stepped up and embraced his cause,” Lisa said.

Jacob was born with hydronephrosis with grade five reflux, or swelling of the kidneys with reverse flow of urine through the ureters that damaged both of his kidneys. When he was 2 days old, blood tests showed that his kidneys were failing, and the next day he had emergency surgery at Presbyterian St. Luke’s Hospital in Denver to replant the ureters, correcting the reflux issue.

For several years, Jacob had stable kidney function, but at a routine appointment when he was 10 years old, he was found to have decreased kidney function. He was prescribed six new medications, had to follow a strict new diet and was scheduled for numerous tests.

By the time he was 15, Jacob’s kidney function started declining again, and he was given the option of dialysis or a transplant.

Lisa did the required testing in late February and found that she was a match for Jacob and donated her kidney to him. They had the surgeries June 25, his at The Children’s Hospital and hers at University Hospital.

“It was from start to finish such an amazing process,” Lisa said. “We had people praying alongside us. Our prayers were answered.”

Following surgery, Jacob, who had been experiencing tiredness and difficulty in concentrating, started feeling energetic again, he said. He will have to wait until he’s fully recovered to return to martial arts, something he’s done for three years. He’s also involved in school theater and likes reading, archery and playing video games, he said.

“I just have a lot more energy. I don’t feel any symptoms or anything,” Jacob said.

Lisa, as the donor, felt some tiredness after surgery but is now recovered, she said.

“As a mother, I would give anything for my children,” Lisa said. “This is a gift I could give. It’s giving him new life.”

Contact Reporter-Herald Staff Writer Shelley Widhalm at 970-669-5050 or swidhalm@reporter-herald.com. Follow her at twitter.com/ShelleyWidhalm.

via Fundraisers set for double kidney transplant recipient – Loveland Reporter-Herald.