Total abdominal wall transplantation for complex transplant cases — experts outline technique Wolters Kluwer Health – EurekAlert (press release)

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May 26, 2017 – For some patients undergoing intestinal or multi-organ transplantation, closing the abdominal wall poses a difficult surgical challenge. Total abdominal wall transplantation provides an alternative for abdominal closure in these complex cases, according to a state-of-the-art approach presented in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

ASPS Member Surgeon David Light, MD, and colleagues of the Cleveland Clinic identify the anatomy and describe a dissection technique for total abdominal wall transplantation. They believe their approach provides a new option for organ transplant recipients with severe abdominal wall defects, when conventional reconstructive techniques aren’t sufficient to close the abdomen.

Experts Outline Approach to Abdominal Wall Transplantation

In some patients undergoing intestinal and/or multiple organ transplants, gaps or defects of the abdominal wall make it difficult to close the abdomen using the patient’s own tissues. Several factors contribute to these problems–particularly the fact that these patients typically have a long history of serious health issues with many previous surgeries.

One study found that traditional abdominal wall closure was not possible in 20 percent of intestinal transplant patients. Partial abdominal wall transplant techniques have been reported, but these do not provide sufficient coverage for the largest abdominal wall defects.

In a series of cadaver dissections, the researchers demonstrate the anatomy of the abdominal wall, with special attention to the four major arteries providing its blood supply. Their paper includes imaging studies illustrating each artery’s contribution to blood flow in the abdominal wall.

The researchers also outline a system classifying the various types of abdominal wall defects and the appropriate options for achieving closure. Conventional reconstructive techniques are suitable for patients with less-extensive defects, Dr. Light and colleagues believe that total abdominal wall transplantation is most appropriate for cases in which the defect comprises at least half of the abdominal wall.

Abdominal wall transplantation is a vascularized composite allotransplant (VCA)–a term referring to transplant procedures combining different types of tissues, such as skin, muscle, and blood vessels. Face and hand transplants are the best-known types of VCA.

Abdominal wall transplantation is an option for patients who are also undergoing organ transplantation–and thus will already be taking lifelong immunosuppressive therapy to prevent transplant rejection. A recent article in Plastic and Reconstructive Surgery reported the successful use of a VCA to reconstruct a complex scalp defect in a patient undergoing a kidney/pancreas transplant.

Dr. Light and coauthors believe that total abdominal wall transplantation should be considered among the alternatives for intestinal or multiple organ transplant patients who have major abdominal wall defects that can’t be managed by conventional reconstructive techniques. The researchers add, “Our algorithm will guide practicing surgeons in the reconstruction of complex abdominal wall defects.”

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Plastic and Reconstructive Surgery® is published by Wolters Kluwer.

Click here to read “Total Abdominal Wall Transplantation: An Anatomical Study and Classification System.”

Article: “Total Abdominal Wall Transplantation: An Anatomical Study and Classification System” (doi: 10.1097/PRS.0000000000003327)

About Plastic and Reconstructive Surgery

For more than 70 years, Plastic and Reconstructive Surgery® (http://www. prsjournal. com/ ) has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. The official journal of the American Society of Plastic Surgeons, Plastic and Reconstructive Surgery® brings subscribers up-to-the-minute reports on the latest techniques and follow-up for all areas of plastic and reconstructive surgery, including breast reconstruction, experimental studies, maxillofacial reconstruction, hand and microsurgery, burn repair, and cosmetic surgery, as well as news on medico-legal issues

About ASPS

The American Society of Plastic Surgeons is the largest organization of board-certified plastic surgeons in the world. Representing more than 7,000 physician members, the Society is recognized as a leading authority and information source on cosmetic and reconstructive plastic surgery. ASPS comprises more than 94 percent of all board-certified plastic surgeons in the United States. Founded in 1931, the Society represents physicians certified by The American Board of Plastic Surgery or The Royal College of Physicians and Surgeons of Canada.

About Wolters Kluwer

Wolters Kluwer N.V. (AEX: WKL) is a global leader in information services and solutions for professionals in the health, tax and accounting, risk and compliance, finance and legal sectors. We help our customers make critical decisions every day by providing expert solutions that combine deep domain knowledge with specialized technology and services.

Wolters Kluwer reported 2016 annual revenues of €4.3 billion. The company, headquartered in Alphen aan den Rijn, the Netherlands, serves customers in over 180 countries, maintains operations in over 40 countries and employs 19,000 people worldwide.

Wolters Kluwer shares are listed on Euronext Amsterdam (WKL) and are included in the AEX and Euronext 100 indices. Wolters Kluwer has a sponsored Level 1 American Depositary Receipt program. The ADRs are traded on the over-the-counter market in the U.S. (WTKWY).

For more information about our solutions and organization, visit http://www. wolterskluwer. com, follow us on Twitter, Facebook, LinkedIn, and YouTube.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

Astros foundation steps up for teen waiting for transplant – KHOU

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HOUSTON – Kayla Aubry is 15-years-old, loves baseball, purple hair and compliments from Houston Astros’ star second baseman, Jose Altuve.

“I like (your hair),” Altuve told the teen on Thursday. 

“(Purple hair) would bring out your eyes,” Kayla replied. “You should try it.”

Altuve, several of his teammates and the Astros Foundation gave Kayla a custom jersey, access to players during batting practice, a signed baseball and premium padded seats to see her hometown Detroit Tigers in person for the first time in years.

Though, deep down, she stared at a full count: one collapsed lung and another failing due to cystic fibrosis.

Doctors gave her five months to live unless she gets a double-lung transplant.

“If you block it out, if you block out the part that you’re pretty much waiting to be told you’re going to live, then it’s okay,” the teen said. “When you think about it and the longer you think about it, you just kind of get depressed.”

She used to dance and ride horses but these days with grueling two-hour breathing treatments, Kayla spends most of her time in a hotel room.

Her dad, Scott, quit job and sold their home in Michigan to keep Kayla at Texas Children’s Hospital where surgeons handle more treatments than anyone in the region.

The Aubrys must stay within 30 miles of the hospital and carry a pager.

If, and when, the device goes off, she will need surgery within an hour. They have been waiting seven months.

“It’s really tough to just block everything out,” Scott Aubry said. “You know, (there are) a lot of restless nights and I hardly sleep.”

That is where Olivia Gray stepped in.

Through the Ronald McDonald House, Gray met and bonded with Kayla. She learned about Kayla’s love for baseball and desire to see the Tigers play. 

So, Gray’s father, Rod, reached out to the Astros Foundation who scored the teen tickets to the one of the Tigers’ games against the Astros at Minute Maid Park.

It is safely within range of the hospital.

“We have the platform to do lots of things for many,” said Twila Carter, executive director of the Astros Foundation. “Certainly she came in a Tigers fan but I think she’s going to leave an Astros fan.”

The teen would prefer to leave for surgery, but being able to enjoy her favorite distraction left her speechless.
 

© 2017 KHOU-TV

Yard sale to raise funds for local transplant patient – Seacoastonline.com

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SEABROOK — A yard sale and bake sale will be held for COTA in honor of Angelique Sanborn, an Exeter-area patient who has had a double lung transplant. The event is planned for Saturday, June 3, from 9 a.m. to 3 p.m. at Trinity United Church, 1 Folly Mill Road, Seabrook.

Angelique, 34, received a double lung transplant at Massachusetts General Hospital in Boston. Funds are being raised to assist with transplant-related expenses.

Donations for the yard sale are being accepted at Trinity United Church on Friday, June 2 from 4 p.m. to 8 p.m. All donations are tax-deductible to the fullest extent of the law and in-kind receipts are available.

Angelique was diagnosed with Cystic Fibrosis. The Sanborn family needs an estimated $40,000 to pay for transplant-related expenses.

“The family and friends of Angelique want to encourage everyone to attend our yard and bake sale and help give Angelique a second chance at life,” said Johanna Cannon. “100 percent of the profits from the yard sale and bake sale will assist with transplant-related expenses.”

For more information about the yard sale and bake sale, or other fundraising and volunteer opportunities, please contact Johanna Cannon 603-661-1978 or Annahoj737@gmail.com.

Angelique Sanborn’s family has asked for assistance from the Children’s Organ Transplant Association (COTA), a national charity based in Bloomington, Indiana. COTA is dedicated to organizing and guiding communities in raising funds for transplant-related expenses. COTA’s services are completely free of charge, and 100 percent of funds generated by COTA community fundraising campaigns are available for transplant-related expenses.

Arizona 10-month-old home, happy and healthy after successful liver transplant – KPNX 12 News TV

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KPNX 12 News TV

KPNX 12 News TV
TEMPE, Ariz. – After a whirlwind and life-saving few months in San Francisco, 10-month-old Elijah Vazquez, is happy, healthy and home in Arizona. Elijah had a successful liver transplant back in the middle of February and just got back to Tempe with  

Heart transplant unites families after Elkhart girl’s death – South Bend Tribune

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SOUTH BEND — Valerie Matthews has taken a painful stroll down County Road 108 in Elkhart every year on May 16 to the spot where her daughter was hit by a pickup truck.
It may be time to stop. For five years, she says, it’s as if she’s been calling out to her 12-year-old daughter, Da’jeianna Smith: “I’m waiting for your heart to walk with me.”
They took that walk this week. Da’jeianna’s transplanted heart now beats inside of 20-year-old Dalton Igoe of Altoona, Pa., who came to visit.
Not only that. On Wednesday, Valerie and Dalton paddled kayaks for the first time in their lives on a pond at St. Patrick’s County Park. And Dalton scaled halfway up a climbing wall at the Family Passport to Play event at the park, then descended, saying, “I guess I’m still not a height person.”
“I can’t believe you did that,” said his mom, Dawn Igoe, as she watched another first-ever event.
“Me neither,” he replied.
None of that would have been possible without Da’jeianna’s heart.
Dalton was born with six congenital heart defects. He lost one lung because of blood clots. He wore a pacemaker to control his heart rate. But the ultimate reason for his transplant was from a condition that his bad heart had triggered: protein-losing enteropathy, where fluids swell in the stomach and, among other things, keep a youth from taking in food, leading to starvation.
He was in desperate shape, swollen and unable to walk. He needed a child’s heart.
After school on May 16, 2012, Valerie drove Da’jeianna back to her Elkhart school, Woodland Elementary, because the girl wanted to play with friends at the playground. Da’jeianna didn’t see her friends, so she began the almost 1-mile hike home along County Road 108. Just over halfway back, at about 5 p.m., a pickup truck hit Da’jeianna. The driver told police that he didn’t see her and that he didn’t realize he’d hit a child until people started shouting at him, according to an initial news report.
Da’jeianna, the second oldest out of four children, died the next day in the hospital. Valerie immediately agreed to donate her daughter’s organs. When Dawn Igoe got word that a transplant was available, she alerted friends, and that afternoon 40 to 50 of them gathered at their house. They prayed for Dalton’s success and for the family, unknown to them, who’d lost a girl.
Valerie knows that one of Da’jeianna’s eyes went to a woman in Elkhart and another to a woman in Chicago. Her kidneys went to two people, and her pancreas to yet another person. But she’s never met them.
The Pennsylvania organization that helped with the transplant, the Center for Organ Recovery and Education, also had brought these two families together for the first time two years ago in Pittsburgh.
That moment, Dalton says, was “surreal.”
“Not much was said in the first 20 minutes,” he recalls.
The families were in separate quarters of a Sheraton Hotel until — with six TV news crews tagging along — they met in a conference room overlooking the Monongahela River.
“A bunch of hugs and emotions running,” Dalton describes. “Just putting a face to the other side for both families.” And saying the words “thank you” and “sorry.”
Each family eventually shared the sagas that had brought them to that moment. But the visit, as part of a conference on organ transplants, was a brief 24 hours.
The next time they saw each other was when Dalton and his mom, Dawn, arrived Monday in Elkhart, starting a three days of emotions.
Monday’s rendezvous at a South Bend Cubs game, where Dalton threw out the first pitch, was joy and excitement “for the fact that we were all together again,” he says.
Tuesday was somber and deep as the families gathered at the site of the accident, where Valerie takes a memorial walk each year on the date of the crash.
“I really hate doing it,” Valerie says, because of what it recalls. She’s since moved to Goshen.
Leading up to it, Dalton was excited, nervous and curious because, until then, all he knew was that “she (Da’jeianna) was hit by a car walking on a road.”
This time, with both families around for support, Valerie walked and shared those accident details that Dalton and his mom didn’t know. And Dalton placed his hand on a memorial cross near the crash site as Valerie covered it with green spray paint to leave his silhouetted mark.
Dawn called her husband that night and couldn’t describe the feeling.
“It finished out what we wanted to realize,” Dalton says. “We experienced what she’s been doing.”
Valerie, who last week added Dalton’s name to the tattoos on her left arm, just over the shoulder from a tattoo of Da’jeianna’s face, says the best part is seeing how Dalton has grown.
“It gives me a sense of peace,” she says. “I can touch her.”
Wednesday began with picnic at the Elkhart cemetery where the girl is buried, a visit to an escape room in Mishawaka and then to St. Pat’s park and later bowling. It was a testament to Dalton’s physical capabilities, which wouldn’t have been possible “if not for the amazing gift.”
As a volunteer firefighter, Dalton also dons up to 120 pounds of gear for 20 or 30 minutes at a time to battle fires. With just one lung, he says, he can handle short periods of physical activity. Hot days make it a challenge, too, which he manages by resting and staying hydrated. Still, he’s joined his family on hikes, including five miles in Acadia National Park in Maine. He couldn’t qualify for sports, but he took up playing the drums, bowling and dancing to jazz and hip hop.
He recently gained certification as an emergency medical technician, or EMT, and began work full time as an ambulance driver, doing medical transports. His early life in and out of hospitals led him to being an EMT, he says, adding, “It’s my way of giving back to everyone who took care of me.”
He also gives 15 to 20 talks a year in Pennsylvania to advocate for organ transplants.
Da’jeianna’s heart does an “amazing” job, says Dalton, who takes the typical series of drugs to keep his body from rejecting it.
But the events of this week, he says, “strengthened both of us; it made us one big family.”
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WFBMC researchers say intellectual disability should not prevent kidney transplants in children – myfox8.com

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myfox8.com

myfox8.com
Transplants for people with intellectual disabilities are a controversial issue. Many centers exclude such patients from consideration for transplants for a variety of reasons, including a decreased life expectancy, a belief that patients with  

Link found between donor, infection in heart, lung transplant recipients – Science Daily

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The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test. Originally, this bacterium was considered to reside exclusively in, and be a potential pathogen of, the area of the reproductive and urinary organs — the genitourinary tract.

“This finding could affect how we approach the evaluation of organ donors,” says Mark Wylam, M.D., who led the team of Mayo Clinic researchers on this study. “If potential transmission of these harmful bacteria can be identified and addressed, the recipient will face a decreased risk of infection and its serious complications. This study shows us that surveillance of both donor and recipient are important in recognizing M. hominis and the infection it can cause.”

Heart and lung transplant recipient infection caused by M. hominis may present with pleurisy (inflammation of membrane in chest cavity and lungs), surgical site infection and mediastinitis (inflammation of tissue in mid-chest). M. hominis resists most antibiotics, and the three antibiotic treatment recommendations for these infections are neither standard for post-transplant recipient care nor are they standard in therapy regimens for surgical site infections.

The study, published recently in EBioMedicine, investigates Mayo Clinic lung and heart-lung transplants between 1998 and July 2015. Seven previously unreported cases of transplant recipients with M. hominis infection were discovered. In each case, pre-transplant sputum cultures had tested negative for M. hominis. Also, a literature review since 1950 found 15 cases of M. hominis infection in lung, heart or heart-lung transplant recipients. The way the germ spread remained uncertain. Given its normal residence in the genitourinary tract, some speculated that infection arose from urinary catheter placement during the transplant surgery.

Mayo investigators noted two particular cases of M. hominis infection that each had received a single lung transplant from the same donor, and no other patients in the hospital were infected by M. hominis. The samples of the M. hominis taken from each infected individual were genetically indistinguishable, suggesting the infections had the same source. This finding, in addition to two other observations, supported the likelihood that M. hominis could be passed from transplant donor to recipient.

Common testing methods have proven insufficient in identifying the bacteria, but the use of polymerase chain reaction detection developed by Robin Patel, M.D., director of Mayo Clinic’s Infectious Diseases Research Laboratory, offers a more time-sensitive and specific test for the bacteria. With this method, researchers zoom in on a certain portion of DNA and then create multiple copies to amplify the segment. Polymerase chain reaction detection reduces the time to detect M. hominis to a few hours, compared to the two to five days needed for a culture media test.

“The true rate of M. hominis infection may actually be higher than what we’ve seen reported,” says Dr. Wylam. “Better detection methods like PCR tests have given us more insight into how common this bacterium is in the airway, which is especially important in heart or lung transplant recipients. More research is needed to learn about these bacteria when it’s found far from its natural home in the genitourinary tract, and especially when it is transmitted to cardiothoracic transplant recipients.”

Story Source:Materials provided by Mayo Clinic. Note: Content may be edited for style and length.

A Night at the Opera: a goodwill concert celebrating organ transplant – WOODTV.com

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WOODTV.com

WOODTV.com
GRAND RAPIDS, Mich. (WOOD) – About 3,000 people are waiting for a life-saving organ in Michigan today. According to the Organ Procurement and Transplantation Network, about 20 people die waiting each day, because the number in need greatly …
Organ transplants in Ontario have increased by 22 per cent in five yearsCanada NewsWire (press release)all 3 news articles »

New Discovery Could Soon Replace The Painful Bone Marrow … – Wall Street Pit

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Wall Street Pit

New Discovery Could Soon Replace The Painful Bone Marrow …
Wall Street Pit
New implant could treat immune and blood disorders without the critical side effects of a traditional bone marrow transplant. May 16, 2017 WSP. human body.

Judge Backs Heart Transplant Program – WUSF News

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WUSF News

WUSF News
Jackson Memorial Hospital, which is approved to perform pediatric heart transplants, also weighed in against the Nicklaus proposal. But Watkins wrote, in part, that approving a certificate of need for Nicklaus wouldn’t harm Jackson Memorial or Joe and more »

Inspiration + Education : . . . . for parents of children who are going through transplant

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