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WFBMC researchers say intellectual disability should not prevent kidney transplants in children – myfox8.com

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myfox8.com

myfox8.com
Transplants for people with intellectual disabilities are a controversial issue. Many centers exclude such patients from consideration for transplants for a variety of reasons, including a decreased life expectancy, a belief that patients with  

Link found between donor, infection in heart, lung transplant recipients – Science Daily

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The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test. Originally, this bacterium was considered to reside exclusively in, and be a potential pathogen of, the area of the reproductive and urinary organs — the genitourinary tract.

“This finding could affect how we approach the evaluation of organ donors,” says Mark Wylam, M.D., who led the team of Mayo Clinic researchers on this study. “If potential transmission of these harmful bacteria can be identified and addressed, the recipient will face a decreased risk of infection and its serious complications. This study shows us that surveillance of both donor and recipient are important in recognizing M. hominis and the infection it can cause.”

Heart and lung transplant recipient infection caused by M. hominis may present with pleurisy (inflammation of membrane in chest cavity and lungs), surgical site infection and mediastinitis (inflammation of tissue in mid-chest). M. hominis resists most antibiotics, and the three antibiotic treatment recommendations for these infections are neither standard for post-transplant recipient care nor are they standard in therapy regimens for surgical site infections.

The study, published recently in EBioMedicine, investigates Mayo Clinic lung and heart-lung transplants between 1998 and July 2015. Seven previously unreported cases of transplant recipients with M. hominis infection were discovered. In each case, pre-transplant sputum cultures had tested negative for M. hominis. Also, a literature review since 1950 found 15 cases of M. hominis infection in lung, heart or heart-lung transplant recipients. The way the germ spread remained uncertain. Given its normal residence in the genitourinary tract, some speculated that infection arose from urinary catheter placement during the transplant surgery.

Mayo investigators noted two particular cases of M. hominis infection that each had received a single lung transplant from the same donor, and no other patients in the hospital were infected by M. hominis. The samples of the M. hominis taken from each infected individual were genetically indistinguishable, suggesting the infections had the same source. This finding, in addition to two other observations, supported the likelihood that M. hominis could be passed from transplant donor to recipient.

Common testing methods have proven insufficient in identifying the bacteria, but the use of polymerase chain reaction detection developed by Robin Patel, M.D., director of Mayo Clinic’s Infectious Diseases Research Laboratory, offers a more time-sensitive and specific test for the bacteria. With this method, researchers zoom in on a certain portion of DNA and then create multiple copies to amplify the segment. Polymerase chain reaction detection reduces the time to detect M. hominis to a few hours, compared to the two to five days needed for a culture media test.

“The true rate of M. hominis infection may actually be higher than what we’ve seen reported,” says Dr. Wylam. “Better detection methods like PCR tests have given us more insight into how common this bacterium is in the airway, which is especially important in heart or lung transplant recipients. More research is needed to learn about these bacteria when it’s found far from its natural home in the genitourinary tract, and especially when it is transmitted to cardiothoracic transplant recipients.”

Story Source:Materials provided by Mayo Clinic. Note: Content may be edited for style and length.

A Night at the Opera: a goodwill concert celebrating organ transplant – WOODTV.com

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WOODTV.com

WOODTV.com
GRAND RAPIDS, Mich. (WOOD) – About 3,000 people are waiting for a life-saving organ in Michigan today. According to the Organ Procurement and Transplantation Network, about 20 people die waiting each day, because the number in need greatly …
Organ transplants in Ontario have increased by 22 per cent in five yearsCanada NewsWire (press release)all 3 news articles »

New Discovery Could Soon Replace The Painful Bone Marrow … – Wall Street Pit

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Wall Street Pit

New Discovery Could Soon Replace The Painful Bone Marrow …
Wall Street Pit
New implant could treat immune and blood disorders without the critical side effects of a traditional bone marrow transplant. May 16, 2017 WSP. human body.

Judge Backs Heart Transplant Program – WUSF News

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WUSF News

WUSF News
Jackson Memorial Hospital, which is approved to perform pediatric heart transplants, also weighed in against the Nicklaus proposal. But Watkins wrote, in part, that approving a certificate of need for Nicklaus wouldn’t harm Jackson Memorial or Joe and more »

Everolimus Reduces Weight Gain in Liver Transplant Recipients – Drug Discovery & Development

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Drug Discovery & Development

Drug Discovery & Development
Researchers from the Intermountain Medical Center Transplant Program found that liver transplant patients taking everolimus (Afinitor) gained less weight – and kept it off at one and two years after starting the drug—than patients taking tacrolimus, … 

John Oliver takes on dialysis, a procedure that’s exhausting, deadly, and very profitable – Vox

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Vox

Vox
It would be far better for DaVita and Fresenius’s patients to get kidney transplants, which extends your lifespan by about 10 years on average, relative to remaining on dialysis, while avoiding exhausting, time-consuming treatment that makes holding

New pill spares women trauma of liver transplant – Daily Mail

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Daily Mail

Daily Mail
‘The 30 to 40 per cent of PBC patients who need Ocaliva are mostly those who have had an early presentation of the disease, and by default from suffering longer they are more likely to need a liver transplant. ‘This drug will make a difference to these  

Doctors use Facebook Live to broadcast Ontario kidney transplant – CTV News

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From election results to Chewbacca mom, Facebook Live has become a popular way to broadcast breaking events as they unfold.

On Wednesday, an Ontario hospital offered a live-streamed look inside an operating room as doctors transplanted a kidney from a wife to her ailing husband.

St. Joseph’s Healthcare Hamilton broadcast the surgery live on Facebook and its website and live-tweeted the event. Viewers were encouraged to ask questions about the procedure as it happened and were answered in real-time by doctors.

The event was intended to be a teachable moment on the science of organ transplants and the importance of kidneys. Local high school students watched in auditoriums, and several thousand Facebook viewers tuned in live.

And there was little left to the imagination. The camera offered an up-close view of the surgery, including the moment the successfully transplanted kidney swelled to a healthy pink and began producing urine.

“It’s peeing! Excellent,” said Dr. Anil Kapoor as he prodded a tube-shaped organ during the livestream.

The kidney recipient was 45-year-old Bhargav Turaga from Hamilton, Ont. His kidney function suddenly deteriorated two years ago, and he required a transplant soon or else face daily dialysis.

His wife, Nagamani Turaga, 44, volunteered her healthy kidney for the procedure.

The event was filled with fascinating factual tidbits. The average adult kidney is about the size of a fist. Doctors have a narrow window – about three minutes – to perfuse or clean the kidney once it’s removed, which preserves it. The kidney sits in a cooler filled with slushy ice while it waits to be transplanted to the recipient.

After all was said and done, Kapoor deemed the surgery a success.

“It was a 10 out of 10, there were no hiccups or complications,” he told the Facebook audience. “The kidney looked beautiful.”

Donor Nagamani will now rest for about four weeks as she recovers from the surgery. A healthy kidney can last about 15 to 20 years, and so it’s likely that Bhargav will require another surgery in the future, according to Dr. Darin Treleaven, medical director of the transplant program at St. Joe’s.

Kapoor said he enjoyed the experience and didn’t feel any extra pressure, despite the online audience.

“We teach residents and medical students and fellows all day long, so we always have an audience in the OR … so it’s really no stretch to do what we did today.”

Duffield first grader receiving transplant from father, support from community – WCYB

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WATCH: Duffield first grader…

In a class full of first graders, Caden Gilbert is hard at work.

However, the kind-hearted 7-year-old has a lot more to focus on than spelling tests and books. On June 8th, Caden will have a kidney transplant. His dad is the donor.

“I would give him both of them if that’s what it took,” Caden’s dad, Christopher Gilbert, said.

It was July 2015. The Gilbert family was coming home from Myrtle Beach only to find that Caden was extremely ill.

After countless tests, doctors told the family he had contacted E. Coli. Things only got worse and that E. Coli eventually turned into a rare disease, which caused kidney failure.

“We had a really hard time accepting it,” Gilbert said. “Going from one week at the beach and talking with your buddies, ‘oh he’s such a big boy I cant wait to be on the sidelines Friday night watching him play football,’ and then a week later we’re in the hospital with him clinging to life.”

Caden went through multiple surgeries and was put on dialysis to treat the syndrome, but nothing took. A transplant now seems like the best option.

“This is not a cure, this is just a treatment,” Caden’s mom, Candi Gilbert, said. “Typically kidney transplants only last 10-15 years from a living donor. I’ve heard cases where they do last a lot longer than that. We just have to wait and see how well we take care of it.”

His supporters want to help during the difficult time and started a fundraiser called “Coins for Caden.”

“Caden is a great kid, he’s a hero, his dad is a hero,” Caden’s principal, Greg Ervin, said.

“It just touches your heart,” Caden’s teacher, Shelly Miller, said. “His story touches your heart, his family touches your heart, and we are privileged to know him and his family. They’ve really touched us this year.”

Everything raised goes to Caden’s COTA (Children’s Organ Transplant Association) fund. It’s money he’ll be able to use for the rest of his life.

If you’d like to support Caden you can donate online by clicking here.

Donations can also be sent to the following address:

ATTN: Coins for Caden
Duffield Primary School
663 Duff-Patt Hwy
Duffield, VA 24244

So far around $3,000 has been raised.